Characterization of Poly (L-co-D,L Lactic Acid) and a Study of Polymer-tissue Interaction in Subcutaneous Implants in Wistar Rats
نویسندگان
چکیده
Faculty of Medical Sciences, Pontifical Catholic University of São Paulo – PUC-SP, CEP 18030-095, Sorocaba, SP, Brazil Department of Physiological Sciences, Faculty of Medical Sciences, Pontifical Catholic University of São Paulo – PUC-SP, CEP 18030-095, Sorocaba, SP, Brazil Department of Materials Engineering, Faculty of Mechanical Engineering, State University of Campinas – UNICAMP, CEP 13083-970, Campinas, SP, Brazil
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Preparation, Characterization and Evaluation of Drug Release Properties of Simvastatin-loaded PLGA Microspheres
Microspheres formulated from poly (D,L-lactic-co-glycolide) (PLGA), a biodegradable polymer, have been extensively evaluated as a drug delivery system. In this study, the preparation, characterization and drug release properties of the PLGA microspheres were evaluated. Simvastatin (SIM)-loaded PLGA microspheres were prepared by oil-in-water emulsion/solvent evaporation method. The microspheres ...
متن کاملPreparation, Characterization and Evaluation of Drug Release Properties of Simvastatin-loaded PLGA Microspheres
Microspheres formulated from poly (D,L-lactic-co-glycolide) (PLGA), a biodegradable polymer, have been extensively evaluated as a drug delivery system. In this study, the preparation, characterization and drug release properties of the PLGA microspheres were evaluated. Simvastatin (SIM)-loaded PLGA microspheres were prepared by oil-in-water emulsion/solvent evaporation method. The microspheres ...
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